Alagebrium Chloride Protects the Heart Against Oxidative Stress in Aging Rats
نویسندگان
چکیده
منابع مشابه
Alagebrium chloride protects the heart against oxidative stress in aging rats.
To investigate the possible effects of alagebrium chloride (ALT-711) on oxidative stress (OS) process in aging hearts, we examined the role of ALT-711 in cardiac function and OS in the heart of aging rats. Increased mitochondrial DNA (mtDNA) deletion as well as nearly a twofold increase in advanced glycation end products (AGEs) accumulation were observed in aging heart, whereas only about 50% o...
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The present experiment was designed to access the effects of Methylmercury chloride (MeHgCl) on antioxidant status, protein concentration, lipid peroxidation and hydroperoxidation in brain parts, spinal cord, lung, heart and pancreas of rats. Twenty male Wistar rats (3 months old) were divided in saline controls (C) and MeHgCl-treated group (MMC). Treated rats were intoxicated with MMC at a dos...
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ژورنال
عنوان ژورنال: The Journals of Gerontology Series A: Biological Sciences and Medical Sciences
سال: 2009
ISSN: 1079-5006,1758-535X
DOI: 10.1093/gerona/glp023